H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect
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© 2020 Elsevier Inc. Burkhart et al. show that mutants lacking components of H3.3 assembly complexes have pleiotropic defects that manifest near the onset of adulthood. Mitochondrial stress likely contributes to these late-onset defects. The late-onset defects of H3.3 assembly mutants can be maternally rescued.
Date issued
2020Department
Howard Hughes Medical Institute; Massachusetts Institute of Technology. Department of BiologyJournal
Current Biology
Publisher
Elsevier BV