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dc.contributor.authorZhang, Xiao-Hui
dc.contributor.authorZhao, Pei-Zhen
dc.contributor.authorKe, Wu-Jian
dc.contributor.authorWang, Liu-Yuan
dc.contributor.authorTso, Lai S.
dc.contributor.authorChen, Zheng-Yu
dc.contributor.authorLiao, Yu-Ying
dc.contributor.authorLiang, Chun-Mei
dc.contributor.authorChen, Hui-Ru
dc.contributor.authorRen, Xu-Qi
dc.contributor.authorHuang, Jin-Mei
dc.contributor.authorOng, Jason J.
dc.contributor.authorYang, Fan
dc.contributor.authorYang, Li-Gang
dc.date.accessioned2021-11-01T14:34:06Z
dc.date.available2021-11-01T14:34:06Z
dc.date.issued2021-07-05
dc.identifier.urihttps://hdl.handle.net/1721.1/136903
dc.description.abstractAbstract Background Mycoplasma genitalium (MG) causes urogenital tract infections and is associated with reproductive morbidity. Although MG has been reported across many regions and population groups, it is not yet routinely tested for in China. Our study contributes to current research by reporting the prevalence and correlates of MG infection in patients attending a sexually transmitted infection (STI) clinic in Guangdong from Jan 2017-May 2018. Methods Urethral (from 489 men) and endo-cervical (from 189 women) samples, blood samples, and patient histories (via questionnaires) were collected. Doctors clinically diagnosed anogenital warts (GW) during the examination (n = 678). The presence of MG was evaluated using an in-house via polymerase chain reaction protocol. We also tested all participants for herpes simplex virus-2 (HSV-2), Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), syphilis and HIV. Univariate and multivariate logistic regression were used to evaluate factors associated with MG. Results MG was detected in 7.2% (49/678) of the patients (men, 7.4%; women, 6.9%). The MG positivity rate was 14.2% among symptomatic patients, and 5.6% for asymptomatic patients, respectively. Only 36.7% (18/49) Mg positive patients were symptomatic. Among the MG-infected patients, 10.2% were co-infected with CT, 6.1% with NG, 8.2% with HSV-2, 4.1% with syphilis and 22.4% with GW. Presentation with clinical symptoms was significantly associated with MG infection [OR = 2.52 (2.03–3.13)]. In our analysis, MG was not associated with other STIs. Conclusions MG is a relatively common infection among individuals attending an STI clinic in Guangdong Province. Routine testing of symptomatic patients may be necessary, and more epidemiological studies are needed to provide evidence for future testing guidelines.en_US
dc.publisherBioMed Centralen_US
dc.relation.isversionofhttps://doi.org/10.1186/s12879-021-06349-4en_US
dc.rightsCreative Commons Attributionen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.sourceBioMed Centralen_US
dc.titlePrevalence and correlates of Mycoplasma genitalium infection among patients attending a sexually transmitted infection clinic in Guangdong, China: a cross-sectional studyen_US
dc.typeArticleen_US
dc.identifier.citationBMC Infectious Diseases. 2021 Jul 05;21(1):649en_US
dc.contributor.departmentMassachusetts Institute of Technology. Anthropology Program
dc.identifier.mitlicensePUBLISHER_CC
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2021-07-11T03:17:58Z
dc.language.rfc3066en
dc.rights.holderThe Author(s)
dspace.date.submission2021-07-11T03:17:58Z
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Needed


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