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dc.contributor.authorWu, D
dc.contributor.authorVoldman, J
dc.date.accessioned2021-11-09T17:07:53Z
dc.date.available2021-11-09T17:07:53Z
dc.date.issued2019-07
dc.identifier.urihttps://hdl.handle.net/1721.1/137986
dc.description.abstract© 2019 IEEE. Protein testing in blood is important for clinical analysis. Traditional blood tests are performed in centralized laboratories and are slow to provide results. In contrast, point-of-care devices deliver rapid results in non-laboratory settings, allowing timely analysis and in turn reducing healthcare costs. Successful point-of-care platforms require seamless integration of chemical assays, fluid management and signal readout. In this regard, we present an integrated, compact and automated electronic system for point-of-care protein sensing. The system comprises of a microfluidics-based electrochemical biosensor, amperometry circuitry and automated microfluidic fluid handling circuitry. This platform utilizes magnetic microbeads to expedite an electronic enzyme-linked immunosorbent assay, and microfluidics to manage small volumes and automate assay operations. A commercial single-chip potentiostat is utilized for amperometry measurements and microfluidics control. Using this all-electrical system, we demonstrate an integrated and automated assay for human interleukin-6.en_US
dc.language.isoen
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en_US
dc.relation.isversionof10.1109/EMBC.2019.8857362en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourceOther repositoryen_US
dc.titleAn integrated and automated electronic system for point-of-care protein testingen_US
dc.typeArticleen_US
dc.identifier.citationWu, D and Voldman, J. 2019. "An integrated and automated electronic system for point-of-care protein testing." Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 2019.
dc.relation.journalProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBSen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/ConferencePaperen_US
eprint.statushttp://purl.org/eprint/status/NonPeerRevieweden_US
dc.date.updated2021-01-25T15:50:21Z
dspace.orderedauthorsWu, D; Voldman, Jen_US
dspace.date.submission2021-01-25T15:50:25Z
mit.journal.volume2019en_US
mit.licenseOPEN_ACCESS_POLICY
mit.metadata.statusAuthority Work and Publication Information Neededen_US


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