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dc.contributor.authorGhotra, Anpreet
dc.contributor.authorKosakowski, Heather L
dc.contributor.authorTakahashi, Atsushi
dc.contributor.authorEtzel, Robin
dc.contributor.authorMay, Markus W
dc.contributor.authorScholz, Alina
dc.contributor.authorJansen, Andreas
dc.contributor.authorWald, Lawrence L
dc.contributor.authorKanwisher, Nancy
dc.contributor.authorSaxe, Rebecca
dc.contributor.authorKeil, Boris
dc.date.accessioned2021-12-01T17:08:49Z
dc.date.available2021-12-01T17:08:49Z
dc.date.issued2021
dc.identifier.urihttps://hdl.handle.net/1721.1/138273
dc.description.abstractPURPOSE: Functional magnetic resonance imaging (fMRI) during infancy poses challenges due to practical, methodological, and analytical considerations. The aim of this study was to implement a hardware-related approach to increase subject compliance for fMRI involving awake infants. To accomplish this, we designed, constructed, and evaluated an adaptive 32-channel array coil. METHODS: To allow imaging with a close-fitting head array coil for infants aged 1-18 months, an adjustable head coil concept was developed. The coil setup facilitates a half-seated scanning position to improve the infant's overall scan compliance. Earmuff compartments are integrated directly into the coil housing to enable the usage of sound protection without losing a snug fit of the coil around the infant's head. The constructed array coil was evaluated from phantom data using bench-level metrics, signal-to-noise ratio (SNR) performances, and accelerated imaging capabilities for both in-plane and simultaneous multislice (SMS) reconstruction methodologies. Furthermore, preliminary fMRI data were acquired to evaluate the in vivo coil performance. RESULTS: Phantom data showed a 2.7-fold SNR increase on average when compared with a commercially available 32-channel head coil. At the center and periphery regions of the infant head phantom, the SNR gains were measured to be 1.25-fold and 3-fold, respectively. The infant coil further showed favorable encoding capabilities for undersampled k-space reconstruction methods and SMS techniques. CONCLUSIONS: An infant-friendly head coil array was developed to improve sensitivity, spatial resolution, accelerated encoding, motion insensitivity, and subject tolerance in pediatric MRI. The adaptive 32-channel array coil is well-suited for fMRI acquisitions in awake infants.en_US
dc.language.isoen
dc.publisherWileyen_US
dc.relation.isversionof10.1002/MRM.28791en_US
dc.rightsCreative Commons Attribution NonCommercial License 4.0en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/en_US
dc.sourceWileyen_US
dc.titleA size‐adaptive 32‐channel array coil for awake infant neuroimaging at 3 Tesla MRIen_US
dc.typeArticleen_US
dc.identifier.citationGhotra, Anpreet, Kosakowski, Heather L, Takahashi, Atsushi, Etzel, Robin, May, Markus W et al. 2021. "A size‐adaptive 32‐channel array coil for awake infant neuroimaging at 3 Tesla MRI." Magnetic Resonance in Medicine, 86 (3).
dc.contributor.departmentMassachusetts Institute of Technology. Department of Brain and Cognitive Sciences
dc.relation.journalMagnetic Resonance in Medicineen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2021-12-01T17:03:28Z
dspace.orderedauthorsGhotra, A; Kosakowski, HL; Takahashi, A; Etzel, R; May, MW; Scholz, A; Jansen, A; Wald, LL; Kanwisher, N; Saxe, R; Keil, Ben_US
dspace.date.submission2021-12-01T17:03:30Z
mit.journal.volume86en_US
mit.journal.issue3en_US
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Neededen_US


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