RNA-Mediated Feedback Control of Transcriptional Condensates
Author(s)
Henninger, Jonathan E; Oksuz, Ozgur; Shrinivas, Krishna; Sagi, Ido; LeRoy, Gary; Zheng, Ming M; Andrews, J Owen; Zamudio, Alicia V; Lazaris, Charalampos; Hannett, Nancy M; Lee, Tong Ihn; Sharp, Phillip A; Cissé, Ibrahim I; Chakraborty, Arup K; Young, Richard A; ... Show more Show less
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© 2020 Elsevier Inc. During the early steps of transcription initiation, nascent RNAs stimulate transcriptional condensate formation, whereas the burst of RNAs produced during elongation stimulates condensate dissolution.
Date issued
2021Department
Whitehead Institute for Biomedical Research; Massachusetts Institute of Technology. Department of Chemical Engineering; Massachusetts Institute of Technology. Department of Biology; Massachusetts Institute of Technology. Department of Physics; Massachusetts Institute of Technology. Department of Chemistry; Massachusetts Institute of Technology. Institute for Medical Engineering & Science; Koch Institute for Integrative Cancer Research at MIT; Ragon Institute of MGH, MIT and HarvardJournal
Cell
Publisher
Elsevier BV
Citation
Henninger, Jonathan E, Oksuz, Ozgur, Shrinivas, Krishna, Sagi, Ido, LeRoy, Gary et al. 2021. "RNA-Mediated Feedback Control of Transcriptional Condensates." Cell, 184 (1).
Version: Author's final manuscript