Automated affinity selection for rapid discovery of peptide binders

Author(s)
Zhang, Genwei; Li, Chengxi; Quartararo, Anthony J; Loas, Andrei; Pentelute, Bradley L
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Abstract
<jats:p>This work reports an automated affinity selection-mass spectrometry (AS-MS) approach amenable to both <jats:italic>de novo</jats:italic> peptide binder discovery and affinity maturation of known binders in a high-throughput and selective manner.</jats:p>
Date issued
2021
URI
https://hdl.handle.net/1721.1/141202
Department
Massachusetts Institute of Technology. Department of Chemistry; Koch Institute for Integrative Cancer Research at MIT; Massachusetts Institute of Technology. Center for Environmental Health Sciences
Journal
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Citation
Zhang, Genwei, Li, Chengxi, Quartararo, Anthony J, Loas, Andrei and Pentelute, Bradley L. 2021. "Automated affinity selection for rapid discovery of peptide binders." Chemical Science, 12 (32).
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