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High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions

Author(s)
Lai, Yong; Cui, Liang; Babunovic, Gregory H; Fortune, Sarah M; Doench, John G; Lu, Timothy K; ... Show more Show less
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Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/
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Abstract
<jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the host.</jats:p>
Date issued
2021
URI
https://hdl.handle.net/1721.1/143758
Department
Singapore-MIT Alliance in Research and Technology (SMART); Massachusetts Institute of Technology. Synthetic Biology Center; Massachusetts Institute of Technology. Research Laboratory of Electronics; Ragon Institute of MGH, MIT and Harvard; Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science; Harvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Department of Biological Engineering
Journal
mBio
Publisher
American Society for Microbiology
Citation
Lai, Yong, Cui, Liang, Babunovic, Gregory H, Fortune, Sarah M, Doench, John G et al. 2021. "High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions." mBio, 12 (6).
Version: Final published version

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