Palladium–peptide oxidative addition complexes for bioconjugation

Author(s)
Rojas, Anthony J; Wolfe, Justin M; Dhanjee, Heemal H; Buslov, Ivan; Truex, Nicholas L; ... Show more
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Abstract
<jats:p>Peptides bearing palladium oxidative addition complexes can be synthesized from the parent aryl halide containing substrates and react with thiol functional groups of small molecules, peptides, and proteins at low micromolar concentrations.</jats:p>
Date issued
2022-10-19
URI
https://hdl.handle.net/1721.1/146551
Department
Massachusetts Institute of Technology. Department of Chemistry; Koch Institute for Integrative Cancer Research at MIT; Massachusetts Institute of Technology. Center for Environmental Health Sciences
Journal
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Citation
Rojas, Anthony J, Wolfe, Justin M, Dhanjee, Heemal H, Buslov, Ivan, Truex, Nicholas L et al. 2022. "Palladium–peptide oxidative addition complexes for bioconjugation." Chemical Science, 13 (40).
Version: Final published version
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