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Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation

Author(s)
Hammam, Elie; Sinha, Ameya; Baumgarten, Sebastian; Nardella, Flore; Liang, Jiaqi; Miled, Samia; Bonhomme, Frédéric; Erdmann, Diane; Arcangioli, Benoit; Arimondo, Paola B; Dedon, Peter; Preiser, Peter; Scherf, Artur; ... Show more Show less
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Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/
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Abstract
<jats:p> <jats:named-content content-type="genus-species">P. falciparum</jats:named-content> is the most virulent malaria parasite species, accounting for the majority of the disease mortality and morbidity. Understanding how this pathogen is able to adapt to different cellular and environmental stressors during its complex life cycle is crucial in order to develop new strategies to tackle the disease. </jats:p>
Date issued
2021
URI
https://hdl.handle.net/1721.1/147797
Department
Massachusetts Institute of Technology. Department of Biological Engineering
Journal
mBio
Publisher
American Society for Microbiology
Citation
Hammam, Elie, Sinha, Ameya, Baumgarten, Sebastian, Nardella, Flore, Liang, Jiaqi et al. 2021. "Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation." mBio, 12 (6).
Version: Final published version

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