Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses

Bordt, Evan A; Shook, Lydia L; Atyeo, Caroline; Pullen, Krista M; De Guzman, Rose M; Meinsohn, Marie-Charlotte; Chauvin, Maeva; Fischinger, Stephanie; Yockey, Laura J; James, Kaitlyn; Lima, Rosiane; Yonker, Lael M; Fasano, Alessio; Brigida, Sara; Bebell, Lisa M; Roberts, Drucilla J; Pépin, David; Huh, Jun R; Bilbo, Staci D; Li, Jonathan Z; Kaimal, Anjali; Schust, Danny J; Gray, Kathryn J; Lauffenburger, Douglas; Alter, Galit; Edlow, Andrea G

Author(s)

Bordt, Evan A; Shook, Lydia L; Atyeo, Caroline; Pullen, Krista M; De Guzman, Rose M; ... Show more

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Abstract

Maternal SARS-CoV-2 infection drives sexually dimorphic placental immune responses and reduces SARS-CoV-2–specific antibody transfer to male fetuses.<

Date issued

2021

URI

https://hdl.handle.net/1721.1/147872

Department

Massachusetts Institute of Technology. Department of Biological Engineering

Journal

Science Translational Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Citation

Bordt, Evan A, Shook, Lydia L, Atyeo, Caroline, Pullen, Krista M, De Guzman, Rose M et al. 2021. "Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses." Science Translational Medicine, 13 (617).

Version: Final published version

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