Observing Nearby Nuclei on Paramagnetic Trityls and MOFs via DNP and Electron Decoupling
Name
Chemistry A European J - 2022 - Tan - Observing Nearby Nuclei on Paramagnetic Trityls and MOFs via DNP and Electron.pdf
Description
Published version
Size
2.81 MB
Format
Adobe PDF
Checksum (MD5)
efd2cd6e5a6436dfefb7c840186c3746
Author(s)
Tan, Kong Ooi
Yang, Luming
Mardini, Michael
Boon Cheong, Choon
Driesschaert, Benoit
Dincă, Mircea
Griffin, Robert G
Date Issued
2022
Journal
Chemistry - A European Journal
Publisher
Wiley
Citation
Tan, Kong Ooi, Yang, Luming, Mardini, Michael, Boon Cheong, Choon, Driesschaert, Benoit et al. 2022. "Observing Nearby Nuclei on Paramagnetic Trityls and MOFs via DNP and Electron Decoupling." Chemistry - A European Journal, 28 (68).
Version
Final published version
Abstract
Dynamic nuclear polarization (DNP) is an NMR sensitivity enhancement technique that mediates polarization transfer from unpaired electrons to NMR-active nuclei. Despite its success in elucidating important structural information on biological and inorganic materials, the detailed polarization-transfer pathway from the electrons to the nearby and then the bulk solvent nuclei, and finally to the molecules of interest-remains unclear. In particular, the nuclei in the paramagnetic polarizing agent play significant roles in relaying the enhanced NMR polarizations to more remote nuclei. Despite their importance, the direct NMR observation of these nuclei is challenging because of poor sensitivity. Here, we show that a combined DNP and electron decoupling approach can facilitate direct NMR detection of these nuclei. We achieved an ∼80 % improvement in NMR intensity via electron decoupling at 0.35 T and 80 K on trityl radicals. Moreover, we recorded a DNP enhancement factor of ϵ ${\varepsilon{} }$ ∼90 and ∼11 % higher NMR intensity using electron decoupling on paramagnetic metal-organic framework, magnesium hexaoxytriphenylene (MgHOTP MOF).
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1002/CHEM.202202556
