Recording and Quantifying C. elegans Behavior
Author(s)
Pokala, Navin; Flavell, Steven W
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Studies of C. elegans behavior have been crucial in identifying genetic pathways that control nervous system development and function, as well as basic principles of neural circuit function. Modern analysis of C. elegans behavior commonly relies on video recordings of animals, followed by automated image analysis and behavior quantification. Here, we describe two methods for recording and quantifying C. elegans behavior: a single-worm tracking approach that provides high-resolution behavioral data for individual animals and a multi-worm tracking approach that allows for quantification of the behavior of many animals in parallel. These approaches should be useful to a wide range of researchers studying the nervous system and behavior of C. elegans.
Date issued
2022Department
Massachusetts Institute of Technology. Department of Brain and Cognitive SciencesPublisher
Springer US
Citation
Pokala, Navin and Flavell, Steven W. 2022. "Recording and Quantifying C. elegans Behavior." 2468.
Version: Author's final manuscript