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dc.contributor.authorDandekar, Raj
dc.contributor.authorWang, Emma
dc.contributor.authorBarbastathis, George
dc.contributor.authorRackauckas, Chris
dc.date.accessioned2023-05-19T14:00:58Z
dc.date.available2023-05-19T14:00:58Z
dc.date.issued2021
dc.identifier.urihttps://hdl.handle.net/1721.1/150781
dc.description.abstract<jats:p> In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it is imperative to address the question: How many infected cases could have been prevented, had the worst affected states not reopened early? To address this question, we have developed a novel COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. The model decomposes the contribution of quarantine strength to the infection time series, allowing us to quantify the role of quarantine control and the associated reopening policies in the US states which showed a major surge in infections. We show that the upsurge in the infected cases seen in these states is strongly corelated with a drop in the quarantine/lockdown strength diagnosed by our model. Further, our results demonstrate that in the event of a stricter lockdown without early reopening, the number of active infected cases recorded on 14 July could have been reduced by more than <jats:inline-formula> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mml:mn>40</mml:mn> <mml:mi>%</mml:mi> </mml:math> </jats:inline-formula> in all states considered, with the actual number of infections reduced being more than <jats:inline-formula> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mml:mn>100,000</mml:mn> </mml:math> </jats:inline-formula> for the states of Florida and Texas. As we continue our fight against COVID-19, our proposed model can be used as a valuable asset to simulate the effect of several reopening strategies on the infected count evolution, for any region under consideration. </jats:p>en_US
dc.language.isoen
dc.publisherAmerican Association for the Advancement of Science (AAAS)en_US
dc.relation.isversionof10.34133/2021/9798302en_US
dc.rightsCreative Commons Attributionen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceAAASen_US
dc.titleImplications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USAen_US
dc.typeArticleen_US
dc.identifier.citationDandekar, Raj, Wang, Emma, Barbastathis, George and Rackauckas, Chris. 2021. "Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA." Health Data Science, 2021.
dc.contributor.departmentMassachusetts Institute of Technology. Department of Mechanical Engineeringen_US
dc.relation.journalHealth Data Scienceen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2023-05-19T13:58:47Z
dspace.orderedauthorsDandekar, R; Wang, E; Barbastathis, G; Rackauckas, Cen_US
dspace.date.submission2023-05-19T13:58:49Z
mit.journal.volume2021en_US
mit.licensePUBLISHER_CC
mit.metadata.statusAuthority Work and Publication Information Neededen_US


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