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dc.contributor.authorCaicedo, H. H.
dc.contributor.authorDarrow, Jonathan J.
dc.contributor.authorCaicedo, Julio C.
dc.contributor.authorPentland, Alex
dc.date.accessioned2023-10-17T14:57:25Z
dc.date.available2023-10-17T14:57:25Z
dc.date.issued2023-09-05
dc.identifier.urihttps://hdl.handle.net/1721.1/152443
dc.description.abstractAbstract Scholars and practitioners have described how investing in health care earlier rather than later can be beneficial, from how “biomarkers” offer promise for early disease detection to healthcare system “incentives” that can promote early preventive medicine. Work by health economists has also made clear that the “health capital” of an individual depreciates over time in the absence of investments in health. Yet, our current policy makers and healthcare system continue prioritizing care of late-stage complex symptomatic illness, often when cure is impossible and disease reversal is improbable, thus exacerbating public health burdens. Critically missing are predicates to address this challenge include the following: first, identifying and validating the specific set of presymptomatic biomarkers that will inform the most appropriate intervention timing for those medical conditions amenable to early intervention; second, shifting fundamental health economic incentives to influence the appropriate disease prevention market; and third, formulating and executing a viable economic framework of reimbursement. We examine these predicates and propose actionable policy recommendations that may help align stakeholder interests to improve public health.en_US
dc.publisherSpringer International Publishingen_US
dc.relation.isversionofhttps://doi.org/10.1007/s43441-023-00569-3en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alikeen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en_US
dc.sourceSpringer International Publishingen_US
dc.titlePrioritizing Early Disease Interventionen_US
dc.typeArticleen_US
dc.identifier.citationCaicedo, H. H., Darrow, Jonathan J., Caicedo, Julio C. and Pentland, Alex. 2023. "Prioritizing Early Disease Intervention."
dc.contributor.departmentMIT Connection Science (Research institute)
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dc.date.updated2023-10-17T03:17:51Z
dc.language.rfc3066en
dc.rights.holderThe Author(s), under exclusive licence to The Drug Information Association, Inc
dspace.embargo.termsY
dspace.date.submission2023-10-17T03:17:51Z
mit.licenseOPEN_ACCESS_POLICY
mit.metadata.statusAuthority Work and Publication Information Neededen_US


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