Resistivity Detection of Perfluoroalkyl Substances (PFAS) with 6 Fluorous-Polyaniline in an Electrical Lateral Flow Sensor
Name
2023-17300RR_Merged_PDF.pdf
Size
1.96 MB
Format
Adobe PDF
Checksum (MD5)
cc7a1327b07b7c36f55c8ebd435a4215
Author(s)
Park, Sohyun
Gordon, Collette T.
Swager, Timothy M.
Date Issued
March 11, 2024
Journal
PNAS
Publisher
PNAS
Citation
Park, Sohyun, Gordon, Collette T. and Swager, Timothy M. 2024. "Resistivity Detection of Perfluoroalkyl Substances (PFAS) with 6 Fluorous-Polyaniline in an Electrical Lateral Flow Sensor." PNAS.
Version
Author's final manuscript
Abstract
Perfluoroalkyl substances (PFAS), known as “forever chemicals,” are a growing concern in the sphere of human and environmental health. In response, rapid, reproducible, and inexpensive methods for PFAS detection in the environment and home water supplies are needed. We have developed a simple and inexpensive perfluoroalkyl acid detection method based on an electrically read lateral flow assay (e-LFA). Our method employs a new fluorous surfactant formulation with undoped polyaniline (F-PANI) fabricated to create test lines for the lateral flow assay. In perfluoroalkyl acid sensing studies, an increase in conductivity of the F-PANI film is caused by acidification and doping of PANI. A conductivity enhancement by 104-fold can be produced by this method and we demonstrate a limit of detection for perfluorooctanoic acid (PFOA) of 400 ppt and perfluorobutanoic acid (PFBA) of 200 ppt. This new method for PFOA detection can be expanded for wide-scale environmental and at-home water testing.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Creative Commons Attribution-Noncommercial-ShareAlike
Persistent DSpace Link
