Expanding the landscape of antibody discovery

Author(s)
Johnson, Shelbe; DeKosky, Brandon J
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Abstract
Library:library screening technologies hold substantial promise for paired antibody:antigen discovery, but challenges have persisted. In this issue of Cell Reports Methods, Wagner et al. introduce a method that combines antibody-ribosome-mRNA complexes, antigen cell surface display, and single-cell RNA sequencing to successfully screen diverse antibody gene libraries against a library of viral receptor proteins.
Date issued
2024-12
URI
https://hdl.handle.net/1721.1/158238
Department
Massachusetts Institute of Technology. Department of Chemical Engineering; Ragon Institute of MGH, MIT and Harvard; Koch Institute for Integrative Cancer Research at MIT
Journal
Cell Reports Methods
Publisher
Elsevier BV
Citation
Johnson, Shelbe and DeKosky, Brandon J. 2024. "Expanding the landscape of antibody discovery." Cell Reports Methods, 4 (12).
Version: Final published version
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