Browsing MIT Open Access Articles by Author "Uchima, Lilen"
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Family-wide analysis of poly(ADP-ribose) polymerase activity
Vyas, Sejal; Matic, Ivan; Uchima, Lilen; Rood, Jenny; Zaja, Roko; e.a. (Nature Publishing Group, 2014-07)The poly(adenosine diphosphate (ADP)-ribose) polymerase (PARP) protein family generates ADP-ribose (ADPr) modifications onto target proteins using NAD[superscript +] as substrate. Based on the composition of three ...