Browsing MIT Open Access Articles by Subject "peptide fragments"
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Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes
(Rockefeller University Press, 2009-10)Shiga-toxigenic Escherichia coli (STEC) use subtilase cytotoxin (SubAB) to interfere with adaptive immunity. Its inhibition of immunoglobulin secretion is both rapid and profound. SubAB favors cleavage of the newly synthesized ...