MIT Open Access Articles: Recent submissions

Now showing items 1-3 of 53865

    • Charge‐Stabilized Nanodiscs as a New Class of Lipid Nanoparticles 

      Pires, Ivan S; Hostetler, Alexander; Covarrubias, Gil; Carlo, Isabella S; Suggs, Jack R; e.a. (Wiley, 2024-11-14)
      Nanoparticles have the potential to improve disease treatment and diagnosis due to their ability to incorporate drugs, alter pharmacokinetics, and enable tissue targeting. While considerable effort is placed on developing ...

    • Pooled Nanoparticle Screening Using a Chemical Barcoding Approach 

      Vaidya, Katherine; Regan, Michael S; Lin, James; Houle, Jenna; Gupta, Aanchal; e.a. (Wiley, 2025-01-27)
      We report the development of a small molecule‐based barcoding platform for pooled screening of nanoparticle delivery. Using aryl halide‐based tags (halocodes), we achieve high‐sensitivity detection via gas chromatography ...

    • High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles 

      Pires, Ivan S; Gordon, Ezra; Suh, Heikyung; Irvine, Darrell J; Hammond, Paula T (Wiley, 2025-04-03)
      Surface modification of nanoparticles (NPs) via the layer‐by‐layer (LbL) technique is a promising approach to generate targeted drug delivery vehicles. LbL‐NPs have been successfully used in preclinical models for controlled ...