MIT Open Access Articles: Recent submissions
Now showing items 13-15 of 53909
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Sustained release of BMP-2 using self-assembled layer-by-layer film-coated implants enhances bone regeneration over burst release
(Elsevier BV, 2022-09)Current clinical products delivering the osteogenic growth factor bone morphogenetic protein 2 (BMP-2) for bone regeneration have been plagued by safety concerns due to a high incidence of off-target effects resulting from ... -
Surface Presentation of Hyaluronic Acid Modulates Nanoparticle–Cell Association
(American Chemical Society, 2022-10-25)Nanoparticle (NP) drug carriers have revolutionized medicine and increased patient quality of life. Clinically approved formulations typically succeed because of reduced off-target toxicity of the cargo. However, increasing ... -
Synergistic combination therapy delivered via layer‐by‐layer nanoparticles induces solid tumor regression of ovarian cancer
(Wiley, 2022-11-08)The majority of patients with high grade serous ovarian cancer (HGSOC) develop recurrent disease and chemotherapy resistance. To identify drug combinations that would be effective in treatment of chemotherapy resistant ...
