Micro(TUBB3)ules Rule in Brain Development
Author(s)Singh, Karuna; Tsai, Li-Huei
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The microtubule network is crucial for the developing nervous system and mutations in tubulin-encoding genes disrupt neuronal migration. In this issue, Tischfield et al. (2010) report that mutations in the neuronal TUBB3 gene have a striking impact on microtubule dynamics resulting in a diverse set of disease symptoms.
DepartmentMassachusetts Institute of Technology. Department of Brain and Cognitive Sciences; Picower Institute for Learning and Memory
Singh, Karuna K. and Li-Huei Tsai. "Micro(TUBB3)ules Rule in Brain Development." Cell, 2010 Jan 8;140(1):74-87.
Author's final manuscript