Internal Friction and Nonequilibrium Unfolding of Polymeric Globules

Author(s)
Wada, Hirofumi; Netz, Roland R.; Alexander-Katz, Alfredo
Thumbnail
DownloadAlexander-Katz-2009-Internal Friction an.pdf (719.3Kb)
PUBLISHER_POLICY
Terms of use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Metadata
Show full item record
Abstract
The stretching response of a single collapsed homopolymer is studied using Brownian dynamic simulations. The irreversibly dissipated work is found to be dominated by internal friction effects below the collapse temperature, and the internal viscosity grows exponentially with the effective cohesive strength between monomers. These results explain friction effects of globular DNA and are relevant for dissipation at intermediate stages of protein folding.
Date issued
2009-07
URI
http://hdl.handle.net/1721.1/51824
Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Journal
Physical Review Letters
Publisher
American Physical Society
Citation
Alexander-Katz, Alfredo , Hirofumi Wada, and Roland R. Netz. “Internal Friction and Nonequilibrium Unfolding of Polymeric Globules.” Physical Review Letters 103.2 (2009): 028102. © 2009 The American Physical Society.
Version: Final published version
ISSN
0031-9007
Collections