Transdermal drug delivery by localized intervention

Author(s)
Weaver, James C.; Herndon, Terry O.; Gowrishankar, Thiruvallur R.
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Abstract
Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free manner. These openings are similar in dimension to commonly experienced scratches and nicks on the skin. These localized openings provide pathways for sustained delivery of drugs either passively using a patch or actively using pressure or iontophoresis.
Date issued
2009-01
URI
http://hdl.handle.net/1721.1/52351
Department
Harvard University--MIT Division of Health Sciences and Technology
Journal
IEEE Engineering in Medicine and Biology Magazine
Publisher
Institute of Electrical and Electronics Engineers
Citation
Gowrishankar, T.R., T.O. Herndon, and J.C. Weaver. “Transdermal drug delivery by localized intervention.” Engineering in Medicine and Biology Magazine, IEEE 28.1 (2009): 55-63. © Copyright 2009 IEEE
Version: Final published version
ISSN
0739-5175
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