dc.contributor.author | Wirth, Dyann | |
dc.contributor.author | Daily, Johanna P. | |
dc.contributor.author | Winzeler, Elizabeth | |
dc.contributor.author | Mesirov, Jill P. | |
dc.contributor.author | Regev, Aviv | |
dc.date.accessioned | 2010-03-12T21:47:49Z | |
dc.date.available | 2010-03-12T21:47:49Z | |
dc.date.issued | 2009-07 | |
dc.identifier.issn | 0027-8424 | |
dc.identifier.uri | http://hdl.handle.net/1721.1/52563 | |
dc.description.abstract | Lemieux et al. (1) describe a reanalysis of our in vivo Plasmodium falciparum patient samples (2), supporting many of our conclusions (exclusive presence of rings, lack of distinct asexual phases in the clusters, a relation between Cluster 1 and gametogenesis). However, Lemieux et al. (1) fit the observed in vivo profiles as a mixture of gametocyte and asexual form mRNA (Fig. 2E in ref. 1), concluding that the discrete clusters are consistent with varying proportions of sexually committed but phenotypically indistinguishable parasites, reflected by the parameter α. | en |
dc.language.iso | en_US | |
dc.publisher | National Academy of Sciences | en |
dc.relation.isversionof | http://dx.doi.org/10.1073/pnas.0904478106 | en |
dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en |
dc.source | PNAS | en |
dc.title | In vivo profiles in malaria are consistent with a novel physiological state | en |
dc.type | Article | en |
dc.identifier.citation | Wirth, Dyann et al. “In vivo profiles in malaria are consistent with a novel physiological state.” Proceedings of the National Academy of Sciences 106.27 (2009): E70. ©2009 the National Academy of Sciences | en |
dc.contributor.department | Broad Institute of MIT and Harvard | en_US |
dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
dc.contributor.approver | Regev, Aviv | |
dc.contributor.mitauthor | Mesirov, Jill P. | |
dc.contributor.mitauthor | Regev, Aviv | |
dc.relation.journal | Proceedings of the National Academy of Sciences of the United States of America | en |
dc.eprint.version | Final published version | en |
dc.identifier.pmid | 19570993 | |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | en |
eprint.status | http://purl.org/eprint/status/PeerReviewed | en |
dspace.orderedauthors | Wirth, D.; Daily, J.; Winzeler, E.; Mesirov, J. P.; Regev, A. | en |
dc.identifier.orcid | https://orcid.org/0000-0001-8567-2049 | |
mit.license | PUBLISHER_POLICY | en |
mit.metadata.status | Complete | |