Polarization sensitive optical coherence tomography of melanin provides tissue inherent contrast based on depolarization
DownloadBaumann-2010-Polarization sensitive optical .pdf (5.635Mb)
PUBLISHER_POLICY
Publisher Policy
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Terms of use
Metadata
Show full item recordAbstract
Polarization sensitive optical coherence tomography (PS-OCT) was used to investigate the polarization properties of melanin. Measurements in samples with varying melanin concentrations revealed polarization scrambling, i.e. depolarization. The results indicate that the depolarizing appearance of pigmented structures like, for instance, the retinal pigment epithelium (RPE) is likely to be caused by the melanin granules contained in these cells.
Date issued
2010-02Department
Massachusetts Institute of Technology. Research Laboratory of ElectronicsJournal
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
Publisher
Society of Photo-optical Instrumentation Engineers
Citation
Baumann, Bernhard et al. “Polarization sensitive optical coherence tomography of melanin provides tissue inherent contrast based on depolarization.” Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV. Ed. Joseph A. Izatt, James G. Fujimoto, & Valery V. Tuchin. San Francisco, California, USA: SPIE, 2010. Vol.7554, 75541M-6. ©2010 SPIE--The International Society for Optical Engineering.
Version: Final published version
ISBN
9780819479501
ISSN
1605-7422
0277-786X