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A microfluidic device to control bio actuators of microorganisms, an application to Vorticella convallaria

Author(s)
Matsudaira, Paul T.; Ryu, Sangjin; Thorsen, Todd A.; Nagai, M.; Fujita, H.
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Abstract
We demonstrate a microfluidic device to control the motion of Vorticella convallaria by changing solution. Floating cells of V. convallaria were injected and cultured inside the device. Approximately 35 cells of V. convallaria in 102 nl of the solution. The cells were treated with saponin solution and controlled with a microfluidic device. When reaction solution was switched, the stalk contracted and relaxed corresponding to the ambient calcium ion concentration change. The length of the stalk changed between 40 and 60 mum, resulting in a working distance of about 20 mum.
Date issued
2009-06
URI
http://hdl.handle.net/1721.1/60016
Department
Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Mechanical Engineering; Whitehead Institute for Biomedical Research
Journal
International Conference on Solid-State Sensors, Actuators, and Microsystems.
Publisher
Institute of Electrical and Electronics Engineers
Citation
Nagai, M. et al. “A microfluidic device to control bio actuators of microorganisms, an application to Vorticella convallaria.” Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International. 2009. 437-440. © 2009, IEEE
Version: Final published version
Other identifiers
E-ISBN: 978-1-4244-4193-8
INSPEC Accession Number: 10916749
ISBN
978-1-4244-4190-7

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