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dc.contributor.authorFaghih, Rose Taj
dc.contributor.authorSavla, Ketan
dc.contributor.authorDahleh, Munther A.
dc.contributor.authorBrown, Emery N.
dc.date.accessioned2011-04-01T17:59:10Z
dc.date.available2011-04-01T17:59:10Z
dc.date.issued2010-09
dc.identifier.isbn978-1-4244-4123-5
dc.identifier.issn1557-170X
dc.identifier.otherINSPEC Accession Number: 11660297
dc.identifier.urihttp://hdl.handle.net/1721.1/62013
dc.description.abstractIn this paper, we revisit the issue of the utility of the FitzHugh-Nagumo (FHN) model for capturing neuron firing behaviors. It has been noted (e.g., see [6]) that the FHN model cannot exhibit certain interesting firing behaviors such as bursting. We illustrate that, by allowing time-varying parameters for the FHN model, one could overcome such limitations while still retaining the low order complexity of the FHN model. We also highlight the utility of the FHN model from an estimation perspective by presenting a novel parameter estimation method that exploits the multiple time scale feature of the FHN model, and compare the performance of this method with the Extended Kalman Filter through illustrative examples.en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (0836720)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (DP1 OD003646)en_US
dc.description.sponsorshipMIT Fellowship in Controlen_US
dc.description.sponsorshipNational Science Foundation (U.S.). Graduate Research Fellowship Programen_US
dc.language.isoen_US
dc.publisherInstitute of Electrical and Electronics Engineersen_US
dc.relation.isversionofhttp://dx.doi.org/10.1109/IEMBS.2010.5627326en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceIEEEen_US
dc.titleThe FitzHugh-Nagumo model: Firing modes with time-varying parameters and parameter estimationen_US
dc.typeArticleen_US
dc.identifier.citationFaghih, R.T. et al. “The Fitzhugh-Nagumo Model: Firing Modes with Time-varying Parameters & Parameter Estimation.” Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE. 2010. 4116-4119. Copyright © 2010, IEEEen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Brain and Cognitive Sciencesen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Scienceen_US
dc.contributor.departmentMassachusetts Institute of Technology. Laboratory for Information and Decision Systemsen_US
dc.contributor.approverDahleh, Munther A.
dc.contributor.mitauthorFaghih, Rose Taj
dc.contributor.mitauthorSavla, Ketan
dc.contributor.mitauthorDahleh, Munther A.
dc.contributor.mitauthorBrown, Emery N.
dc.relation.journalInternational Conference IEEE Engineering in Medicine and Biology Society (EMBC)en_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/ConferencePaperen_US
dspace.orderedauthorsFaghih, R T; Savla, K; Dahleh, M A; Brown, E Nen
dc.identifier.orcidhttps://orcid.org/0000-0003-2668-7819
dc.identifier.orcidhttps://orcid.org/0000-0002-1470-2148
dc.identifier.orcidhttps://orcid.org/0000-0002-9959-8422
mit.licensePUBLISHER_POLICYen_US
mit.metadata.statusComplete


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