| dc.contributor.author | Sancak, Yasemin | |
| dc.contributor.author | Sabatini, David | |
| dc.date.accessioned | 2011-08-31T19:25:14Z | |
| dc.date.available | 2011-08-31T19:25:14Z | |
| dc.date.issued | 2009-01 | |
| dc.date.submitted | 2008-09 | |
| dc.identifier.issn | 0300-5127 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/65577 | |
| dc.description.abstract | The serum- and nutrient-sensitive protein kinase mTOR (mammalian target of rapamycin) is a master regulator of cell growth and survival. The mechanisms through which nutrients regulate mTOR have been one of the major unanswered questions in the mTOR field. Identification of the Rag (Ras-related GTPase) family of GTPases as mediators of amino acid signalling to mTOR is an important step towards our understanding of this mechanism. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (R01 CA103866) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (AI47389) | en_US |
| dc.description.sponsorship | United States. Dept. of Defense (grant number W81XWH-07-0448) | en_US |
| dc.description.sponsorship | W. M. Keck Foundation | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Biomedical Society | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1042/bst0370289 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | Portland Press | en_US |
| dc.title | Rag proteins regulate amino-acid-induced mTORC1 signalling | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Sancak, Yasemin, and David M. Sabatini. “Rag Proteins Regulate Amino-acid-induced mTORC1 Signalling.” Biochemical Society Transactions 37.1 (2009) : 289-290. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Biology | en_US |
| dc.contributor.department | Whitehead Institute for Biomedical Research | en_US |
| dc.contributor.department | Koch Institute for Integrative Cancer Research at MIT | en_US |
| dc.contributor.approver | Sabatini, David M. | |
| dc.contributor.mitauthor | Sabatini, David M. | |
| dc.contributor.mitauthor | Sancak, Yasemin | |
| dc.relation.journal | Biochemical Society Transactions | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Sancak, Yasemin; Sabatini, David M. | en |
| dc.identifier.orcid | https://orcid.org/0000-0002-1446-7256 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
