| dc.contributor.author | Lou, Sha | |
| dc.contributor.author | Fu, Gregory C. | |
| dc.date.accessioned | 2011-09-21T19:09:09Z | |
| dc.date.available | 2011-09-21T19:09:09Z | |
| dc.date.issued | 2010-03 | |
| dc.date.submitted | 2010-02 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/65912 | |
| dc.description.abstract | A new family of organometallic compounds, organozirconium reagents, are shown to serve as suitable partners in cross-coupling reactions of (activated) secondary alkyl electrophiles. Thus, the first catalytic method for coupling secondary α-bromoketones with alkenylmetal reagents has been developed, specifically, a mild, versatile, and stereoconvergent carbon−carbon bond-forming process that generates potentially labile β,γ-unsaturated ketones with good enantioselectivity. | en_US |
| dc.description.sponsorship | National Institute of General Medical Sciences (U.S.) (grant R01-GM62871) | en_US |
| dc.description.sponsorship | Novartis (Firm) | en_US |
| dc.description.sponsorship | Merck Research Laboratories | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society | en_US |
| dc.relation.isversionof | http:/dx.doi.org/10.1021/ja1017046 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | Prof. Fu | en_US |
| dc.title | Enantioselective Alkenylation via Nickel-Catalyzed Cross-Coupling with Organozirconium Reagents | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Lou, Sha, and Gregory C. Fu. “Enantioselective Alkenylation via Nickel-Catalyzed Cross-Coupling with Organozirconium Reagents.” Journal of the American Chemical Society 132.14 (2010) : 5010-5011. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.approver | Fu, Gregory C. | |
| dc.contributor.mitauthor | Lou, Sha | |
| dc.contributor.mitauthor | Fu, Gregory C. | |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Lou, Sha; Fu, Gregory C. | en |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
