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dc.contributor.authorRibbeck, Katharina
dc.date.accessioned2011-11-16T21:25:17Z
dc.date.available2011-11-16T21:25:17Z
dc.date.issued2009-08
dc.date.submitted2009-07
dc.identifier.issn1756-2392
dc.identifier.urihttp://hdl.handle.net/1721.1/67040
dc.description.abstractI propose a mechanism by which viruses successfully infect new individuals, despite being immotile particles with no ability for directed movement. Within cells, viral particle movements are directed by motors and elements of the cytoskeleton, but how viruses cross extracellular barriers, like mucus, remains a mystery. I propose that viruses cross these barriers by hitch-hiking on bacteria or sperm cells which can transport themselves across mucosal layers designed to protect the underlying cells from pathogen attack. An important implication of this hypothesis is that agents that block interactions between viruses and bacteria or sperm may be new tools for disease prevention.en_US
dc.description.sponsorshipNational Institute of Mental Health (U.S.) (grant P50 GM068763-06)en_US
dc.language.isoen_US
dc.publisherElsevier Ltd.en_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.bihy.2009.07.004en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alike 3.0en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.sourcePubMed Centralen_US
dc.titleDo viruses use vectors to penetrate mucus barriers?en_US
dc.typeArticleen_US
dc.identifier.citationRibbeck, Katharina. “Do viruses use vectors to penetrate mucus barriers?” Bioscience Hypotheses 2 (2009): 359-362. Web. 16 Nov. 2011. © 2011 Elsevier Ltd.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Biological Engineeringen_US
dc.contributor.approverRibbeck, Katherina
dc.contributor.mitauthorRibbeck, Katharina
dc.relation.journalBioscience Hypothesesen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsRibbeck, Katharinaen
dc.identifier.orcidhttps://orcid.org/0000-0001-8260-338X
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


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