| dc.contributor.author | Smith, Sean W. | |
| dc.contributor.author | Fu, Gregory C. | |
| dc.date.accessioned | 2011-12-15T14:35:50Z | |
| dc.date.available | 2011-12-15T14:35:50Z | |
| dc.date.issued | 2009-09 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/67692 | |
| dc.description.abstract | A chiral phosphine catalyzes the addition of a carbon nucleophile to the γ position of an electron-poor allene (amide-, ester-, or phosphonate-substituted), in preference to isomerization to a 1,3-diene, in good ee and yield. This strategy provides an attractive method for the catalytic asymmetric γ functionalization of carbonyl (and related) compounds. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (National Institute of General Medical Sciences, Grant R01-GM57034) | en_US |
| dc.description.sponsorship | Merck Research Laboratories | en_US |
| dc.description.sponsorship | Novartis (Firm) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja9061823 | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | Prof. Fu via Diane Johansen | en_US |
| dc.title | Asymmetric Carbon-Carbon Bond Formation gamma to a Carbonyl Group: Phosphine-Catalyzed Addition of Nitromethane to Allenes | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Smith, Sean W., and Gregory C. Fu. “Asymmetric Carbon−Carbon Bond Formation γ to a Carbonyl Group: Phosphine-Catalyzed Addition of Nitromethane to Allenes.” Journal of the American Chemical Society 131.40 (2009): 14231-14233. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.approver | Fu, Gregory C. | |
| dc.contributor.mitauthor | Smith, Sean W. | |
| dc.contributor.mitauthor | Fu, Gregory C. | |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Smith, Sean W.; Fu, Gregory C. | en |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
