Thalamic activity that drives visual cortical plasticity
Author(s)
Linden, Monica L.; Heynen, Arnold J.; Haslinger, Robert Heinz; Bear, Mark
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Manipulations of activity in one retina can profoundly affect binocular connections in the visual cortex. Retinal activity is relayed to the cortex by the dorsal lateral geniculate nucleus (dLGN). We compared the qualities and amount of activity in the dLGN following monocular eyelid closure and monocular retinal inactivation in awake mice. Our findings substantially alter the interpretation of previous studies and define the afferent activity patterns that trigger cortical plasticity.
Date issued
2009-04Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences; Picower Institute for Learning and MemoryJournal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Linden, Monica L. et al. “Thalamic Activity That Drives Visual Cortical Plasticity.” Nature Neuroscience 12.4 (2009): 390–392.
Version: Author's final manuscript
ISSN
1097-6256
1546-1726