Ultrafast High-pressure AC Electro-osmotic Pumps for Portable Biomedical Microfluidics
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Thorsen_Main_Rev_Composite.pdf
Size
1.19 MB
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Checksum (MD5)
63ebba968bc395507673828bacfbb7d3
Author(s)
Huang, Chien-Chih
Bazant, Martin Z.
Thorsen, Todd A.
Date Issued
October 2009
Journal
Lab on a Chip
Publisher
Royal Society of Chemistry (RSC Publishing)
Citation
Huang, Chien-Chih, Martin Z. Bazant, and Todd Thorsen. “Ultrafast high-pressure AC electro-osmotic pumps for portable biomedical microfluidics.” Lab on a Chip 10.1 (2010): 80.
Version
Author's final manuscript
Abstract
This paper details the development of an integrated AC electro-osmotic (ACEO) microfluidic pump for dilute electrolytes consisting of a long serpentine microchannel lined with three dimensional (3D) stepped electrode arrays. Using low AC voltage (1 V rms, 1 kHz), power (5 mW) and current (4.5 mA) in water, the pump is capable of generating a 1.3 kPa head pressure, a 100-fold increase over prior ACEO pumps, and a 1.3 mm/s effective slip velocity over the electrodes without flow reversal. The integrated ACEO pump can utilize low ionic strength solutions such as distilled water as the working solution to pump physiological strength (100 mM) biological solutions in separate microfluidic devices, with potential applications in portable or implantable biomedical microfluidic devices. As a proof-of-concept experiment, the use of the ACEO pumps for DNA hybridization in a microfluidic microarray is demonstrated.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Mathematics
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1039/b915979g
