Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration
Author(s)Chauhan, Vikash P.; Popovic, Zoran; Chen, Ou; Cui, Jian; Fukumura, Dai; Bawendi, Moungi G.; Jain, Rakesh K.; ... Show more Show less
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Shape dependent: Fluorescent quantum-dot-based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real-time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half-life.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
Angewandte Chemie International Edition
Wiley Blackwell (John Wiley & Sons)
Chauhan, Vikash P. et al. “Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration.” Angewandte Chemie International Edition 50.48 (2011): 11417–11420.
Author's final manuscript