Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration

Author(s)
Chauhan, Vikash P.; Popovic, Zoran; Chen, Ou; Cui, Jian; Fukumura, Dai; ... Show more
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Abstract
Shape dependent: Fluorescent quantum-dot-based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real-time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half-life.
Date issued
2011-10
URI
http://hdl.handle.net/1721.1/72121
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Angewandte Chemie International Edition
Publisher
Wiley Blackwell (John Wiley & Sons)
Citation
Chauhan, Vikash P. et al. “Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration.” Angewandte Chemie International Edition 50.48 (2011): 11417–11420.
Version: Author's final manuscript
ISSN
1433-7851
1521-3773
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