Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography

Author(s)
Srinivasan, Vivek J.; Sakadžic, Sava; Gorczynska, Iwona; Ruvinskaya, Svetlana; Wu, Weicheng; ... Show more
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Abstract
We describe depth-resolved microscopy of cortical hemodynamics with high-speed spectral/Fourier domain optical coherence tomography (OCT). Stimulus-evoked changes in blood vessel diameter, flow, and total hemoglobin were measured in the rat somatosensory cortex. The results show OCT measurements of hemodynamic changes during functional activation and represent an important step toward understanding functional hyperemia at the microscopic level.
Date issued
2009-10
URI
http://hdl.handle.net/1721.1/72569
Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Journal
Optics Letters
Publisher
Optical Society of America
Citation
Srinivasan, Vivek J. et al. “Depth-resolved Microscopy of Cortical Hemodynamics with Optical Coherence Tomography.” Optics Letters 34.20 (2009): 3086.
Version: Author's final manuscript
ISSN
0146-9592
1539-4794
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