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Regenerative Medicine: Learning from Past Examples

Author(s)
Couto, Daniela S.; Perez-Breva, Luis; Cooney, Charles L.
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.

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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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Abstract
Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge and others mature. We propose a framework that analyzes technological developments along with alternative business models and illustrates how to use both strategically to map value capture by companies in regenerative medicine. We analyze how to balance flexibility of the supply chain and clarity in the regulatory pathway for each business model and propose the possible pathways of evolution between business models. We also drive analogies between cell-based therapies and other healthcare products such as biologicals and medical devices and suggest how to strategically evolve from these areas into the cell therapy space.
Date issued
2012-06
URI
http://hdl.handle.net/1721.1/72661
Department
Massachusetts Institute of Technology. Center for Biomedical Innovation; Massachusetts Institute of Technology. Department of Chemical Engineering
Journal
Tissue Engineering. Part A
Publisher
Mary Ann Liebert
Citation
Couto, Daniela S., Luis Perez-Breva, and Charles L. Cooney. “Regenerative Medicine: Learning from Past Examples.” Tissue Engineering Part A (2012): 120725085622009. Copyright © 2012 Mary Ann Liebert, Inc. publishers.
Version: Final published version
ISSN
1937-3341
1937-335X

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