Show simple item record

dc.contributor.authorJones, Kevin C.
dc.contributor.authorGanim, Ziad
dc.contributor.authorPeng, Chunte
dc.contributor.authorTokmakoff, Andrei
dc.date.accessioned2012-10-12T15:20:41Z
dc.date.available2012-10-12T15:20:41Z
dc.date.issued2012-01
dc.date.submitted2011-09
dc.identifier.issn0740-3224
dc.identifier.issn1520-8540
dc.identifier.urihttp://hdl.handle.net/1721.1/73929
dc.description.abstractMultidimensional spectroscopies provide increased spectral information but time resolution is often limited by the picosecond lifetimes of the transitions they probe. At the expense of additional complexity, transient multidimensional techniques extend the accessible timescales for studying nonequilibrium chemical and biophysical phenomena. Transient temperature-jump (T-jump) experiments are particularly versatile, since they can be applied to any temperature-dependent change of state. We have developed a method to correct transient nonlinear techniques for distortions resulting from transient linear absorption of the probing pulses, distortions which can lead to false interpretations of the data. We apply these corrections in the collection of T-jump transient two dimensional infrared spectra for the peptides diglycine and the beta-hairpin peptide trpzip2. For diglycine, the T-jump induces changes in H-bonding, a response which is inherent to all aqueous systems. The trpzip2 results probe the hairpin unfolding kinetics and reveal two time scales: <10 ns increased flexibility and 1:1 mus beta-hairpin disordering.en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant CHE-0616575)en_US
dc.description.sponsorshipNational Science Foundation (U.S.) (Grant CHE-0911107)en_US
dc.language.isoen_US
dc.publisherOptical Society of Americaen_US
dc.relation.isversionofhttp://dx.doi.org/10.1364/JOSAB.29.000118en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceProf. Tokmakoff via Erja Kajosaloen_US
dc.titleTransient two-dimensional spectroscopy with linear absorption corrections applied to temperature-jump two-dimensional infrareden_US
dc.typeArticleen_US
dc.identifier.citationJones, Kevin C. et al. “Transient Two-dimensional Spectroscopy with Linear Absorption Corrections Applied to Temperature-jump Two-dimensional Infrared.” Journal of the Optical Society of America B 29.1 (2011): 118. Web.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.approverTokmakoff, Andrei
dc.contributor.mitauthorTokmakoff, Andrei
dc.contributor.mitauthorJones, Kevin C.
dc.contributor.mitauthorGanim, Ziad
dc.contributor.mitauthorPeng, Chunte
dc.relation.journalJournal of the Optical Society of America Ben_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsJones, Kevin C.; Ganim, Ziad; Peng, Chunte Sam; Tokmakoff, Andreien
mit.licensePUBLISHER_POLICYen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record