| dc.contributor.author | Akbey, Umit |  | 
| dc.contributor.author | Franks, W. Trent |  | 
| dc.contributor.author | Linden, Arne |  | 
| dc.contributor.author | Lange, Sascha |  | 
| dc.contributor.author | Griffin, Robert Guy |  | 
| dc.contributor.author | van Rossum, Barth-Jan |  | 
| dc.contributor.author | Oschkinat, Harmut |  | 
| dc.date.accessioned | 2012-11-06T22:19:16Z |  | 
| dc.date.available | 2012-11-06T22:19:16Z |  | 
| dc.date.issued | 2010-08 |  | 
| dc.identifier.issn | 0570-0833 |  | 
| dc.identifier.issn | 1521-3773 |  | 
| dc.identifier.issn | 1433-7851 |  | 
| dc.identifier.uri | http://hdl.handle.net/1721.1/74582 |  | 
| dc.description.abstract | For D's a jolly good fellow: Deuteration of proteins significantly increases the signal enhancements observed in dynamic nuclear polarization (DNP) magic-angle spinning (MAS) NMR experiments. In 13C CP-MAS spectra an enhancement of 120 is observed for perdeuterated SH3 with an exchangeable proton ratio of 50 %, whereas the enhancement is only 31 for the fully protonated SH3. The direct 13C excitation of the perdeuterated sample increases the enhancement to 148. | en_US | 
| dc.language.iso | en_US |  | 
| dc.publisher | Wiley-Blackwell Pubishers | en_US | 
| dc.relation.isversionof | http://dx.doi.org/10.1002/anie.201002044 | en_US | 
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US | 
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US | 
| dc.source | Prof. Griffin via Erja Kajosalo | en_US | 
| dc.title | Dynamic Nuclear Polarization of Deuterated Proteins | en_US | 
| dc.type | Article | en_US | 
| dc.identifier.citation | Akbey, Ümit et al. “Dynamic Nuclear Polarization of Deuterated Proteins.” Angewandte Chemie International Edition 49.42 (2010): 7803–7806. Web. | en_US | 
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US | 
| dc.contributor.department | Francis Bitter Magnet Laboratory (Massachusetts Institute of Technology) | en_US | 
| dc.contributor.approver | Griffin, Robert Guy |  | 
| dc.contributor.mitauthor | Griffin, Robert Guy |  | 
| dc.relation.journal | Angewandte Chemie International Edition | en_US | 
| dc.eprint.version | Author's final manuscript | en_US | 
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US | 
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US | 
| dspace.orderedauthors | Akbey, Ümit; Franks, W. Trent; Linden, Arne; Lange, Sascha; Griffin, Robert G.; van Rossum, Barth-Jan; Oschkinat, Hartmut | en | 
| dc.identifier.orcid | https://orcid.org/0000-0003-1589-832X |  | 
| mit.license | OPEN_ACCESS_POLICY | en_US | 
| mit.metadata.status | Complete |  |