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Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery

dc.contributor.authorPark, Ji-Ho
dc.contributor.authorvon Maltzahn, Geoffrey
dc.contributor.authorOng, Luvena L.
dc.contributor.authorCentrone, Andrea
dc.contributor.authorHatton, T. Alan
dc.contributor.authorRuoslahti, Erkki
dc.contributor.authorBhatia, Sangeeta N.
dc.contributor.authorSailor, Michael J.
dc.date.accessioned2012-12-10T13:44:50Z
dc.date.available2012-12-10T13:44:50Z
dc.date.issued2009-11
dc.date.submitted2009-08
dc.identifier.issn0935-9648
dc.identifier.issn1521-4095
dc.identifier.urihttp://hdl.handle.net/1721.1/75307
dc.descriptionAuthor Manuscript: 2011 March 15.en_US
dc.description.abstractA cooperative nanosystem consisting of two distinct nanomaterials works in vivo to detect tumor tissues and deliver drugs to the site. Gold nanorods (GNRs) localize to the tumor region, where they report their location and convert near-infrared radiation to thermal energy. Circulating thermally labile therapeutic liposomes respond to the thermal signal, releasing their drug payload selectively in the GNR-populated tumor.en_US
dc.description.sponsorshipNational Cancer Institute (U.S.) (U54 CA 119335 UCSD CCNE)en_US
dc.description.sponsorshipNational Cancer Institute (U.S.) (Grant 5-R01-CA124427)en_US
dc.description.sponsorshipNational Cancer Institute (U.S.) (Grant U54 CA119349 MIT CCNE)en_US
dc.description.sponsorshipMoores Cancer Centeren_US
dc.description.sponsorshipNanoTUMOR Centeren_US
dc.language.isoen_US
dc.publisherWiley Blackwellen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/adma.200902895en_US
dc.rightsCreative Commons Attribution-Noncommercial-Share Alike 3.0en_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/en_US
dc.sourcePMCen_US
dc.titleCooperative nanoparticles for tumor detection and photothermally triggered drug deliveryen_US
dc.typeArticleen_US
dc.identifier.citationPark, Ji-Ho et al. “Cooperative Nanoparticles for Tumor Detection and Photothermally Triggered Drug Delivery.” Advanced Materials 22.8 (2010): 880–885.en_US
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.mitauthorHatton, T. Alan
dc.contributor.mitauthorBhatia, Sangeeta N.
dc.relation.journalAdvanced Materialsen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsPark, Ji-Ho; von Maltzahn, Geoffrey; Ong, Luvena L.; Centrone, Andrea; Hatton, T. Alan; Ruoslahti, Erkki; Bhatia, Sangeeta N.; Sailor, Michael J.en
dc.identifier.orcidhttps://orcid.org/0000-0002-1293-2097
dc.identifier.orcidhttps://orcid.org/0000-0002-4558-245X
mit.licenseOPEN_ACCESS_POLICYen_US
mit.metadata.statusComplete


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