| dc.contributor.author | Palde, Prakash B. | |
| dc.contributor.author | Jamison, Timothy F. | |
| dc.date.accessioned | 2013-01-16T19:41:17Z | |
| dc.date.available | 2013-01-16T19:41:17Z | |
| dc.date.issued | 2011-03 | |
| dc.date.submitted | 2011-02 | |
| dc.identifier.issn | 0044-8249 | |
| dc.identifier.issn | 1521-3757 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/76267 | |
| dc.description.abstract | Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad substrate scope. The hazards associated with HN[subscript 3] are essentially eliminated, shock-sensitive metal azides such as Zn(N[subscript 3])[subscript 2] are avoided, and residual NaN[subscript 3] is quenched in-line with NaNO[subscript 2]. | en_US |
| dc.description.sponsorship | Novartis Foundation (MIT Center for Continuous Manufacturing) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley Blackwell | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/anie.201006272 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.source | Prof. Jamison via Erja Kajosalo | en_US |
| dc.title | Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Palde, Prakash B., and Timothy F. Jamison. “Safe and Efficient Tetrazole Synthesis in a Continuous-Flow Microreactor.” Angewandte Chemie International Edition 50.15 (2011): 3525–3528. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.approver | Jamison, Timothy F. | |
| dc.contributor.mitauthor | Palde, Prakash B. | |
| dc.contributor.mitauthor | Jamison, Timothy F. | |
| dc.relation.journal | Angewandte Chemie | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Palde, Prakash B.; Jamison, Timothy F. | en |
| dc.identifier.orcid | https://orcid.org/0000-0002-8601-7799 | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
