| dc.contributor.author | Taylor, Alexander M. | |
| dc.contributor.author | Altman, Ryan A. | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2013-11-01T14:51:29Z | |
| dc.date.available | 2013-11-01T14:51:29Z | |
| dc.date.issued | 2009-07 | |
| dc.date.submitted | 2009-05 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/81936 | |
| dc.description.abstract | The enantioselective α-arylation and α-vinylation of oxindoles catalyzed by Pd and a biarylmonophosphine ligand with both axial and phosphorus-based chirogenicity is reported. The resultant quaternary carbon stereocenters are formed in high enantiomeric excess, and the conditions tolerate a range of substitution on both the oxindole and the aryl/vinyl coupling partners. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (GM46059) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Predoctoral Fellowship F31GM081905) | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.description.sponsorship | Boehringer Ingelheim Pharmaceuticals | en_US |
| dc.description.sponsorship | Merck & Co. | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja903880q | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | Palladium-Catalyzed Enantioselective α-Arylation and α-Vinylation of Oxindoles Facilitated by an Axially Chiral P-Stereogenic Ligand | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Taylor, Alexander M., Ryan A. Altman, and Stephen L. Buchwald. “Palladium-Catalyzed Enantioselective α-Arylation and α-Vinylation of Oxindoles Facilitated by an Axially Chiral P-Stereogenic Ligand.” Journal of the American Chemical Society 131, no. 29 (July 29, 2009): 9900-9901. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Taylor, Alexander M. | en_US |
| dc.contributor.mitauthor | Altman, Ryan A. | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Taylor, Alexander M.; Altman, Ryan A.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
