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Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions

Author(s)
Teverovskiy, Georgiy; Surry, David S.; Buchwald, Stephen Leffler
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Abstract
Good to excellent yields of aryl trifluoromethyl sulfides, which are an important class of compounds in both the pharmaceutical and agrochemical areas, can be achieved under mild conditions by the Pd-catalyzed reaction of aryl bromides with a trifluoromethylthiolate nucleophile (see scheme).
Date issued
2011-06
URI
http://hdl.handle.net/1721.1/81964
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Angewandte Chemie International Edition
Publisher
Wiley Blackwell
Citation
Teverovskiy, Georgiy, David S. Surry, and Stephen L. Buchwald. “Pd-Catalyzed Synthesis of Ar-SCF3 Compounds under Mild Conditions.” Angewandte Chemie International Edition 50, no. 32 (August 1, 2011): 7312-7314.
Version: Author's final manuscript
ISSN
14337851
1521-3773

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