| dc.contributor.author | Maimone, Thomas | |
| dc.contributor.author | Kinzel, Tom | |
| dc.contributor.author | Zhang, Yong | |
| dc.contributor.author | Takase, Michael K. | |
| dc.contributor.author | Milner, Phillip John | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2013-11-04T15:22:13Z | |
| dc.date.available | 2013-11-04T15:22:13Z | |
| dc.date.issued | 2011-10 | |
| dc.date.submitted | 2011-09 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/81966 | |
| dc.description.abstract | A mechanistic investigation of the Pd-catalyzed conversion of aryl triflates to fluorides is presented. Studies reveal that C–F reductive elimination from a LPd[superscript II](aryl)F complex (L = t-BuBrettPhos or RockPhos) does not occur when the aryl group is electron rich. Evidence is presented that a modified phosphine, generated in situ, serves as the actual supporting ligand during catalysis with such substrates. A preliminary study of the reactivity of a LPd[superscript II](aryl)F complex based on this modified ligand is reported. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (GM46059) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Postdoctoral Fellowship 1F32GM088931) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Grant CHE 9808061) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Grant DBI 9729592) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (CHE-0946721) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja208461k | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | Evidence for in Situ Catalyst Modification during the Pd-Catalyzed Conversion of Aryl Triflates to Aryl Fluorides | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Maimone, Thomas J., Phillip J. Milner, Tom Kinzel, Yong Zhang, Michael K. Takase, and Stephen L. Buchwald. “Evidence for in Situ Catalyst Modification during the Pd-Catalyzed Conversion of Aryl Triflates to Aryl Fluorides.” Journal of the American Chemical Society 133, no. 45 (November 16, 2011): 18106-18109. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Materials Science and Engineering | en_US |
| dc.contributor.mitauthor | Maimone, Thomas | en_US |
| dc.contributor.mitauthor | Milner, Phillip John | en_US |
| dc.contributor.mitauthor | Kinzel, Tom | en_US |
| dc.contributor.mitauthor | Zhang, Yong | en_US |
| dc.contributor.mitauthor | Takase, Michael K. | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Maimone, Thomas J.; Milner, Phillip J.; Kinzel, Tom; Zhang, Yong; Takase, Michael K.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| dspace.mitauthor.error | true | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
