| dc.contributor.author | Trenkle, James D. | |
| dc.contributor.author | Jamison, Timothy F. | |
| dc.date.accessioned | 2013-11-13T14:21:44Z | |
| dc.date.available | 2013-11-13T14:21:44Z | |
| dc.date.issued | 2009-06 | |
| dc.date.submitted | 2009-04 | |
| dc.identifier.issn | 14337851 | |
| dc.identifier.issn | 1521-3773 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/82095 | |
| dc.description.abstract | Ringing the changes: The total synthesis of the title compound centers around a novel strategy that employs a nickel(0)–phosphine complex and triethyl borane in an efficient closure of a 14-membered ring through C--C bond formation (see scheme; cod=cyclooctadiene). The synthesis was accomplished in 10 steps and in approximately 9 % overall yield. | en_US |
| dc.description.sponsorship | National Institute of General Medical Sciences (U.S.) (GM-72566) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (CHE-9809061) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (DBI-9729592) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (1S10RR13866-01) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley Blackwell | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/anie.200902079 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Macrocyclization by Nickel-Catalyzed, Ester-Promoted, Epoxide-Alkyne Reductive Coupling: Total Synthesis of (−)-Gloeosporone | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Trenkle, James D., and Timothy F. Jamison. “Macrocyclization by Nickel-Catalyzed, Ester-Promoted, Epoxide-Alkyne Reductive Coupling: Total Synthesis of (−)-Gloeosporone.” Angewandte Chemie International Edition 48, no. 29 (July 6, 2009): 5366-5368. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Trenkle, James D. | en_US |
| dc.contributor.mitauthor | Jamison, Timothy F. | en_US |
| dc.relation.journal | Angewandte Chemie International Edition | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Trenkle, James D.; Jamison, Timothy F. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0002-8601-7799 | |
| dspace.mitauthor.error | true | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
