A Versatile Catalyst System for Suzuki−Miyaura Cross-Coupling Reactions of C(sp[superscript 2])-Tosylates and Mesylates

Author(s)
Bhayana, Brijesh; Fors, Brett P.; Buchwald, Stephen Leffler
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Abstract
A catalyst system for the Suzuki−Miyaura cross-coupling reactions of aryl and vinyl tosylates and mesylates has been developed. This catalyst displays excellent functional group tolerance and allows the coupling of heteroarylboronic acids with aryl tosylates and mesylates to be performed in high yields. Moreover, reactions employing alkylboronic acids, as well as heteroaryl, vinyl, and allylic pinacol boronate esters, were conducted with high efficiencies.
Date issued
2009-08
URI
http://hdl.handle.net/1721.1/82100
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Organic Letters
Publisher
American Chemical Society (ACS)
Citation
Bhayana, Brijesh, Brett P. Fors, and Stephen L. Buchwald. “A Versatile Catalyst System for Suzuki−Miyaura Cross-Coupling Reactions of C(sp2)-Tosylates and Mesylates.” Organic Letters 11, no. 17 (September 3, 2009): 3954-3957.
Version: Author's final manuscript
ISSN
1523-7060
1523-7052
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