A Versatile Catalyst System for Suzuki−Miyaura Cross-Coupling Reactions of C(sp[superscript 2])-Tosylates and Mesylates
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Author(s)
Bhayana, Brijesh
Fors, Brett P.
Buchwald, Stephen Leffler
Date Issued
August 2009
Journal
Organic Letters
Publisher
American Chemical Society (ACS)
Citation
Bhayana, Brijesh, Brett P. Fors, and Stephen L. Buchwald. “A Versatile Catalyst System for Suzuki−Miyaura Cross-Coupling Reactions of C(sp2)-Tosylates and Mesylates.” Organic Letters 11, no. 17 (September 3, 2009): 3954-3957.
Version
Author's final manuscript
Abstract
A catalyst system for the Suzuki−Miyaura cross-coupling reactions of aryl and vinyl tosylates and mesylates has been developed. This catalyst displays excellent functional group tolerance and allows the coupling of heteroarylboronic acids with aryl tosylates and mesylates to be performed in high yields. Moreover, reactions employing alkylboronic acids, as well as heteroaryl, vinyl, and allylic pinacol boronate esters, were conducted with high efficiencies.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ol9015892
