Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals
Author(s)Ho, Chun-Yu; Chan, Chun-Wa; Schleicher, Kristin D.; Jamison, Timothy F.
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Recent advances using nickel complexes in the activation of unactivated monosubstituted olefins for catalytic intermolecular carbon-carbon bond-forming reactions with carbonyl compounds, such as simple aldehydes, isocyanates, and conjugated aldehydes and ketones, are discussed. In these reactions, the olefins function as vinyl- and allylmetal equivalents, providing a new strategy for organic synthesis. Current limitations and the outlook for this new strategy are also discussed.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
Thieme Publishing Group
Ho, Chun-Yu, Kristin Schleicher, Chun-Wa Chan, and Timothy Jamison. “Catalytic Addition of Simple Alkenes to Carbonyl Compounds by Use of Group 10 Metals.” Synlett 2009, no. 16 (October 4, 2009): 2565-2582.
Author's final manuscript