| dc.contributor.author | Medley, Jonathan William | |
| dc.contributor.author | Movassaghi, Mohammad | |
| dc.date.accessioned | 2013-11-18T20:32:57Z | |
| dc.date.available | 2013-11-18T20:32:57Z | |
| dc.date.issued | 2012-05 | |
| dc.date.submitted | 201-01 | |
| dc.identifier.issn | 14337851 | |
| dc.identifier.issn | 1521-3773 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/82466 | |
| dc.description.abstract | Building cycles: A strategy for the concise, stereoselective synthesis of aspidosperma alkaloids and related structures via a common putative diiminium ion intermediate is reported. The approach enables the dimerization of aspidosperma-type structures at the sterically hindered C2 position. The intermediate is prepared in one step from the shown lactam through an electrophilic double-cyclization cascade (see scheme; Tf=trifluoromethanesulfonyl). | en_US |
| dc.description.sponsorship | National Institute of General Medical Sciences (U.S.) (GM074825) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley Blackwell | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/anie.201200387 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | A Concise and Versatile Double-Cyclization Strategy for the Highly Stereoselective Synthesis and Arylative Dimerization of Aspidosperma Alkaloids | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Medley, Jonathan William, and Mohammad Movassaghi. “A Concise and Versatile Double-Cyclization Strategy for the Highly Stereoselective Synthesis and Arylative Dimerization of Aspidosperma Alkaloids.” Angewandte Chemie International Edition 51, no. 19 (May 7, 2012): 4572-4576. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Medley, Jonathan William | en_US |
| dc.contributor.mitauthor | Movassaghi, Mohammad | en_US |
| dc.relation.journal | Angewandte Chemie International Edition | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Medley, Jonathan William; Movassaghi, Mohammad | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3080-1063 | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
