| dc.contributor.author | Lathrop, Stephen | |
| dc.contributor.author | Kim, Justin | |
| dc.contributor.author | Movassaghi, Mohammad | |
| dc.date.accessioned | 2013-11-22T14:17:23Z | |
| dc.date.available | 2013-11-22T14:17:23Z | |
| dc.date.issued | 2012-06 | |
| dc.identifier.issn | 0009-4293 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/82539 | |
| dc.description | The doi doesn't seem to work, but it is the correct one. | en_US |
| dc.description.abstract | Concise and general strategies for radical-based dimerization of cyclotryptamine and cyclotryptophan derivatives in addition to radical-based oxidation of structurally complex diketopiperazines are discussed. The impact of these radical-based chemistries on the rapid generation of molecular complexity is highlighted using representative examples from recent complex homodimeric alkaloid total syntheses. Additionally, a new and general strategy for radical-based directed heterodimerization of cyclotryptamine substructures via solvent-caged unsymmetrical diazene fragmentation is discussed. | en_US |
| dc.description.sponsorship | National Institute of General Medical Sciences (U.S.) (GM089732) | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.description.sponsorship | Camille & Henry Dreyfus Foundation | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Swiss Chemical Society | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.2533/chimia.2012.389 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike 3.0 | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Radical-mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Lathrop, Stephen Paul; Kim, Justin; Movassaghi, Mohammad. Chimia (Aarau). 2012; 66(6): 389–393. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Lathrop, Stephen | en_US |
| dc.contributor.mitauthor | Kim, Justin | en_US |
| dc.contributor.mitauthor | Movassaghi, Mohammad | en_US |
| dc.relation.journal | CHIMIA International Journal for Chemistry | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Lathrop, Stephen Paul; Kim, Justin; Movassaghi, Mohammad. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3080-1063 | |
| dspace.mitauthor.error | true | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
