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Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays

Author(s)
Hook, Andrew L.; Chang, Chien-Yi; Yang, Jing; Atkinson, Steve; Davies, Martyn C.; Williams, Paul; Alexander, Morgan R.; Anderson, Daniel Griffith; Langer, Robert S; ... Show more Show less
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Abstract
A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacterial material. The coverage of three bacterial species, Pseudomonas aeruginosa, Staphylococcus aureus, and uropathogenic Escherichia coli is assessed.
Date issued
2013-02
URI
http://hdl.handle.net/1721.1/82883
Department
Harvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Department of Chemical Engineering; Koch Institute for Integrative Cancer Research at MIT
Journal
Advanced Materials
Publisher
Wiley Blackwell
Citation
Hook, Andrew L., Chien-Yi Chang, Jing Yang, Steve Atkinson, Robert Langer, Daniel G. Anderson, Martyn C. Davies, Paul Williams, and Morgan R. Alexander. “Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays.” Advanced Materials 25, no. 18 (May 14, 2013): 2542-2547. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Version: Final published version
ISSN
09359648
1521-4095

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