Putting Two Heads Together to Unwind DNA

Author(s)
Takara, Thomas J.; Bell, Stephen P.; Takara,Thomas J.
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Abstract
The loading of replicative helicases onto DNA is tightly regulated in all organisms, yet the molecular mechanisms for this event remain poorly defined. Remus et al. (2009) provide important insights into helicase loading in eukaryotes, showing that the Mcm2–7 replicative helicase encircles double-stranded DNA as head-to-head double hexamers.
Date issued
2009-11
URI
http://hdl.handle.net/1721.1/83085
Department
Massachusetts Institute of Technology. Department of Biology
Journal
Cell
Publisher
Elsevier B.V.
Citation
Takara, Thomas J., and Stephen P. Bell. “Putting Two Heads Together to Unwind DNA.” Cell 139, no. 4 (November 2009): 652-654. http://dx.doi.org/10.1016/j.cell.2009.10.037. © 2009 Elsevier Inc.
Version: Final published version
ISSN
00928674
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